Interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens.

Interferon-gamma (Ifnγ), a key macrophage activating cytokine, plays pleiotropic roles in host immunity. In this study, the ability of Ifnγ to induce the aggregation of resident mouse adherent peritoneal exudate cells (APECs), consisting primarily of macrophages, was investigated. Cell-cell interact...

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Bibliographic Details
Main Authors: Bhagawat S Chandrasekar, Shikha Yadav, Emmanuel S Victor, Shamik Majumdar, Mukta Deobagkar-Lele, Nitin Wadhwa, Santosh Podder, Mrinmoy Das, Dipankar Nandi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4452304?pdf=render