Computational Verification of Large Logical Models—Application to the Prediction of T Cell Response to Checkpoint Inhibitors

At the crossroad between biology and mathematical modeling, computational systems biology can contribute to a mechanistic understanding of high-level biological phenomenon. But as knowledge accumulates, the size and complexity of mathematical models increase, calling for the development of efficient...

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Bibliographic Details
Main Authors: Céline Hernandez, Morgane Thomas-Chollier, Aurélien Naldi, Denis Thieffry
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.558606/full