MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT
Abstract Background Aberrant hyperactivation of epithelial proliferation, AKT signaling, and association with unopposed estrogen (E2) exposure is the most common endometrial cancer dysfunction. In the normal uterus, progesterone (P4) inhibits proliferation by coordinating stromal-epithelial cross-ta...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-018-4502-7 |