Preparation and Evaluation of Poly(Ethylene Glycol)–Poly(Lactide) Micelles as Nanocarriers for Oral Delivery of Cyclosporine A

Preparation and Evaluation of Poly(Ethylene Glycol)–Poly(Lactide) Micelles as Nanocarriers for Oral Delivery of Cyclosporine A

<p>Abstract</p> <p>A series of monomethoxy poly(ethylene glycol)&#8211;poly(lactide) (mPEG&#8211;PLA) diblock copolymers were designed according to polymer&#8211;drug compatibility and synthesized, and mPEG&#8211;PLA micelle was fabricated and used as a nanocarrier...

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Bibliographic Details
Main Authors: Huang Yanqing, Zhang Yanhui, Li Xinru, Zhou Yanxia, Wang Xiaoning, Fan Yating, Liu Yan
Format: Article
Language:English
Published: SpringerOpen 2010-01-01
Series:Nanoscale Research Letters
Subjects:
Monomethoxy poly(ethylene glycol)&#8211;poly(lactide)
Polymeric micelles
Cyclosporine A
Solubility parameter
In vitro release
Intestinal absorption
Online Access:http://dx.doi.org/10.1007/s11671-010-9583-4

Internet

http://dx.doi.org/10.1007/s11671-010-9583-4

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