Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS
Angiotensin II (AII) plays a major role in the progression of inflammation and NADPH-derived oxidative stress (OS) in several tissues. The brain possesses a local angiotensin system, and OS and inflammation are key factors in the progression of Parkinson's disease. In rat mesencephalic cultures...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996108000533 |