Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistence

Abstract Reverse transcription of HIV-1 results in the generation of a linear cDNA that serves as the precursor to the integrated provirus. Other classes of extrachromosomal viral cDNA molecules can be found in acutely infected cells including the 1-LTR and 2-LTR circles of viral DNA, also referred...

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Bibliographic Details
Main Authors: Javier Martinez-Picado, Ryan Zurakowski, María José Buzón, Mario Stevenson
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Retrovirology
Online Access:http://link.springer.com/article/10.1186/s12977-018-0398-1