Mineralocorticoid receptors in the pathophysiology of vascular inflammation and atherosclerosis.

Atherosclerosis is a chronic inflammatory disease of the vasculature that causes significant morbidity and mortality from myocardial infarction, stroke, peripheral vascular disease, and heart failure. Landmark clinical trials revealed that mineralocorticoid receptor (MR) antagonists improve outcomes...

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Bibliographic Details
Main Authors: Mary Elizabeth Moss, Iris Z Jaffe
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00153/full