Functional Analysis of Glycosylation of Zika Virus Envelope Protein

Summary: Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. The ZIKV envelope (E) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. Like other flaviviruses, the ZIKV E protein is glycosylated at amino aci...

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Main Authors: Camila R. Fontes-Garfias, Chao Shan, Huanle Luo, Antonio E. Muruato, Daniele B.A. Medeiros, Elizabeth Mays, Xuping Xie, Jing Zou, Christopher M. Roundy, Maki Wakamiya, Shannan L. Rossi, Tian Wang, Scott C. Weaver, Pei-Yong Shi
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717314481