Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance
Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces. Here we show that knockout mice of Shootin1 display abnormal projection of the forebrain commissural...
Main Authors: | Kentarou Baba, Wataru Yoshida, Michinori Toriyama, Tadayuki Shimada, Colleen F Manning, Michiko Saito, Kenji Kohno, James S Trimmer, Rikiya Watanabe, Naoyuki Inagaki |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/34593 |
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