The regulation of the AdcR regulon in Streptococcus pneumoniae depends both on Zn2+- and Ni2+ -availability

By using a transcriptomic approach, we have elucidated the effect of Ni2+ on the global gene expression of S. pneumoniae D39 by identifying several differentially expressed genes/operons in the presence of a high extracellular concentration of Ni2+. The genes belonging to the AdcR regulon (adcRCBA,...

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Bibliographic Details
Main Authors: Irfan eManzoor, Sulman eShafeeq, Muhammad eAfzal, Oscar P. Kuipers
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00091/full