Various Emetogens Increase the Secretion of Salivary Amylase in Rats: a Potential Model in Emesis Research

We investigated the effects of various emetic agents: cisplatin, apomorphine, lithium chloride (LiCl), rolipram, sibutramine, and the β3-adrenoceptor (AR) agonist CL316243 on salivary amylase secretion in rats. We also determined the inhibitory effect of granisetron, a 5-HT3–receptor antagonist, on...

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Bibliographic Details
Main Authors: Hideo Fukui, Eri Miwa, Takako Iwachido, Harumi Kitaura, Hatsue Furukawa
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319309405