Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral

Abstract Background Adaptive changes in cis-regulatory elements are an essential component of evolution by natural selection. Identifying adaptive and functional noncoding DNA elements throughout the genome is therefore crucial for understanding the relationship between phenotype and genotype. Resul...

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Bibliographic Details
Main Authors: Alejandro Berrio, Ralph Haygood, Gregory A. Wray
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-6752-4