A genomic safe haven for mutant complementation in Cryptococcus neoformans.

Just as Koch's postulates formed the foundation of early infectious disease study, Stanley Falkow's molecular Koch's postulates define best practice in determining whether a specific gene contributes to virulence of a pathogen. Fundamentally, these molecular postulates state that if a...

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Bibliographic Details
Main Authors: Samantha D M Arras, Jessica L Chitty, Kirsten L Blake, Benjamin L Schulz, James A Fraser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391909?pdf=render