Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

Developing an in vitro blood-brain-barrier (BBB) model that reproduces the organ’s complex structure and function is an open challenge. Here the authors present a BBB-on-a-chip that includes endothelial cells, pericytes and a 3D astrocytic network which resembles the morphology and function of astro...

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Bibliographic Details
Main Authors: Song Ih Ahn, Yoshitaka J. Sei, Hyun-Ji Park, Jinhwan Kim, Yujung Ryu, Jeongmoon J. Choi, Hak-Joon Sung, Tobey J. MacDonald, Allan I. Levey, YongTae Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13896-7

Internet

https://doi.org/10.1038/s41467-019-13896-7

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