An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.

An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.

The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored. Here, we report that the E3 ubiquitin ligase Cul7(Fbxw8) localizes to the Golgi c...

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Bibliographic Details
Main Authors: Nadia Litterman, Yoshiho Ikeuchi, Gilbert Gallardo, Brenda C O'Connell, Mathew E Sowa, Steven P Gygi, J Wade Harper, Azad Bonni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21572988/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21572988/pdf/?tool=EBI

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