Synthesis and in vitro anti-proliferative capabilities of steroidal thiazole and indole derivatives

Derivatives (1–15) of steroidal and indole class were synthesized using different strategies. These compounds were characterized by 1H NMR spectroscopy and EI-MS, respectively. The synthetic derivatives were examined for their cytotoxic effects on human adenocarcinoma cells (HCT-116) using 3-(4,5-di...

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Bibliographic Details
Main Authors: Fariha Shamim, Kanwal, Firdos Alam Khan, Muhammad Taha, Khalid Mohammed Khan, Arshia
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610319300481