Cell Type-Specific Annotation and Fine Mapping of Variants Associated With Brain Disorders

Common genetic variants confer susceptibility to a large number of complex brain disorders. Given that such variants predominantly localize in non-coding regions of the human genome, there is a significant challenge to predict and characterize their functional consequences. More importantly, most av...

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Bibliographic Details
Main Authors: Abolfazl Doostparast Torshizi, Iuliana Ionita-Laza, Kai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.575928/full