Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation

Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation

The amyloid-β 1-42 (Aβ1-42) peptide is produced by proteolytic cleavage of the amyloid precursor protein (APP) by sequential reactions that are catalyzed by γ and β secretases. Aβ1-42, together with the Tau protein are two principal hallmarks of Alzheime...

Full description

Bibliographic Details
Main Authors: Daniel Miguel Ángel Villalobos Acosta, Brenda Chimal Vega, José Correa Basurto, Leticia Guadalupe Fragoso Morales, Martha Cecilia Rosales Hernández
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s
beta amyloid 1-42
S-shape
oligomerization
Online Access:http://www.mdpi.com/1422-0067/19/8/2415

Internet

http://www.mdpi.com/1422-0067/19/8/2415

Similar Items