HDAC Inhibitors Exert Anti-Myeloma Effects through Multiple Modes of Action

HDACs are critical regulators of gene expression that function through histone modification. Non-histone proteins and histones are targeted by these proteins and the inhibition of HDACs results in various biological effects. Moreover, the aberrant expression and function of these proteins is thought...

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Bibliographic Details
Main Authors: Yoichi Imai, Mitsuhito Hirano, Masayuki Kobayashi, Muneyoshi Futami, Arinobu Tojo
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/4/475