Dysregulation of complement system and CD4+ T cell activation pathways implicated in allergic response.

Dysregulation of complement system and CD4+ T cell activation pathways implicated in allergic response.

Allergy is a complex disease that is likely to involve dysregulated CD4+ T cell activation. Here we propose a novel methodology to gain insight into how coordinated behaviour emerges between disease-dysregulated pathways in response to pathophysiological stimuli. Using peripheral blood mononuclear c...

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Bibliographic Details
Main Authors: Alexessander Couto Alves, Sören Bruhn, Adaikalavan Ramasamy, Hui Wang, John W Holloway, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, Mikael Benson, David J Balding, Lachlan J M Coin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792967?pdf=render

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http://europepmc.org/articles/PMC3792967?pdf=render

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