Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.

Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.

Leucine-rich repeat containing 10 (LRRC10) is a cardiac-specific protein exclusively expressed in embryonic and adult cardiomyocytes. However, the role of LRRC10 in mammalian cardiac physiology remains unknown. To determine if LRRC10 is critical for cardiac function, Lrrc10-null (Lrrc10(-/-)) mice w...

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Bibliographic Details
Main Authors: Matthew J Brody, Timothy A Hacker, Jitandrakumar R Patel, Li Feng, Junichi Sadoshima, Sergei G Tevosian, Ravi C Balijepalli, Richard L Moss, Youngsook Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517560?pdf=render

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http://europepmc.org/articles/PMC3517560?pdf=render

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