Accelerated Partial Breast Irradiation: Macrophage Polarisation Shift Classification Identifies High-Risk Tumours in Early Hormone Receptor-Positive Breast Cancer

Accelerated Partial Breast Irradiation: Macrophage Polarisation Shift Classification Identifies High-Risk Tumours in Early Hormone Receptor-Positive Breast Cancer

Studies have demonstrated correlations between accumulations of tumour-associated macrophages (TAMs), especially of M2-like phenotype, and increased mortality in advanced breast cancer. We investigated the prognostic potential of both main macrophage phenotypes in early hormone receptor-positive (HR...

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Bibliographic Details
Main Authors: Sören Schnellhardt, Ramona Erber, Maike Büttner-Herold, Marie-Charlotte Rosahl, Oliver J. Ott, Vratislav Strnad, Matthias W. Beckmann, Lillian King, Arndt Hartmann, Rainer Fietkau, Luitpold Distel
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
tumour associated macrophages
cd68
cd163
prognosis
early breast cancer
hormone receptor-positive
accelerated partial breast irradiation
Online Access:https://www.mdpi.com/2072-6694/12/2/446

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https://www.mdpi.com/2072-6694/12/2/446

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