Higher TLR7 Gene Expression Predicts Poor Clinical Outcome in Advanced NSCLC Patients Treated with Immunotherapy

Higher TLR7 Gene Expression Predicts Poor Clinical Outcome in Advanced NSCLC Patients Treated with Immunotherapy

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of lung cancer. However, their clinical benefit is limited to a minority of patients. To unravel immune-related factors that are predictive of sensitivity or resistance to immunotherapy, we performed a gene expression analysis by...

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Bibliographic Details
Main Authors: Sara Baglivo, Fortunato Bianconi, Giulio Metro, Alessio Gili, Francesca Romana Tofanetti, Guido Bellezza, Biagio Ricciuti, Martina Mandarano, Valeria Teti, Annamaria Siggillino, Maria Sole Reda, Rita Chiari, Lorenza Pistola, Angelo Sidoni, Vincenzo Minotti, Fausto Roila, Vienna Ludovini
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
non-small-cell lung cancer (NSCLC)
predictive biomarkers
immune gene expression
immunotherapy
immune checkpoint inhibitor (ICI)
PD-L1
Online Access:https://www.mdpi.com/2073-4425/12/7/992

Internet

https://www.mdpi.com/2073-4425/12/7/992

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