Targeting determinants of dosage compensation in Drosophila.

The dosage compensation complex (DCC) in Drosophila melanogaster is responsible for up-regulating transcription from the single male X chromosome to equal the transcription from the two X chromosomes in females. Visualization of the DCC, a large ribonucleoprotein complex, on male larval polytene chr...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-02-01
Series:PLoS Genetics
Online Access:http://dx.doi.org/10.1371/journal.pgen.0020005