Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns
The increased number of annotated bacterial genomes provides a vast resource for genome mining. Several bacterial natural products with epoxide groups have been identified as pre-mRNA spliceosome inhibitors and antitumor compounds through genome mining. These epoxide-containing natural products feat...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2016-06-01
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| Series: | Synthetic and Systems Biotechnology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X16300023 |