Chotosan, a Kampo Formula, Ameliorates Hippocampal LTD and Cognitive Deficits in Juvenile-Onset Diabetes Rats

Chotosan, a Kampo Formula, Ameliorates Hippocampal LTD and Cognitive Deficits in Juvenile-Onset Diabetes Rats

Childhood-onset type 1 diabetes is associated with modest impairments in cognition and has an elevated risk of cognitive decline. Our previous study showed that working memory and hippocampal long-term depression (LTD) were impaired in juvenile-onset diabetes mellitus (JDM) rats. In this study, we i...

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Bibliographic Details
Main Authors: Sachie Sasaki-Hamada, Keita Tamaki, Hayuma Otsuka, Tatsuto Ueno, Hiroaki Sacai, Yimin Niu, Kinzo Matsumoto, Jun-Ichiro Oka
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319302026

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http://www.sciencedirect.com/science/article/pii/S1347861319302026

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