Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes

Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes

Zika virus (ZIKV) infection in the human central nervous system (CNS) causes Guillain–Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune response cells in the CNS and an important component of the blood–brain barrier. Consequently, any damage to astrocytes facilitates th...

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Bibliographic Details
Main Authors: Jianhong Sun, Wanpo Zhang, Zhongyuan Tan, Caishang Zheng, Yan Tang, Xianliang Ke, Yuan Zhang, Yan Liu, Penghui Li, Qinxue Hu, Hanzhong Wang, Panyong Mao, Zhenhua Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Virulence
Subjects:
zika virus
connective tissue growth factor/nephroblastoma overexpressed (ccn) gene family 1(ccn1)
ca2+/calmodulin-dependent protein kinase ii
camp-responsive element-binding protein (creb)
camp response element
ns3 protein
Online Access:http://dx.doi.org/10.1080/21505594.2020.1715189

Internet

http://dx.doi.org/10.1080/21505594.2020.1715189

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