Assessment of HIV-1 integration in tissues and subsets across infection stages

Assessment of HIV-1 integration in tissues and subsets across infection stages

The integration of HIV DNA into the host genome contributes to lifelong infection in most individuals. Few studies have examined integration in lymphoid tissue, where HIV predominantly persists before and after antiretroviral treatment (ART). Of particular interest is whether integration site distri...

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Bibliographic Details
Main Authors: Vincent H. Wu, Christopher L. Nobles, Leticia Kuri-Cervantes, Kevin McCormick, John K. Everett, Son Nguyen, Perla M. del Rio Estrada, Mauricio González-Navarro, Fernanda Torres-Ruiz, Santiago Ávila-Ríos, Gustavo Reyes-Terán, Frederic D. Bushman, Michael R. Betts
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-12-01
Series:JCI Insight
Subjects:
AIDS/HIV
Immunology
Online Access:https://doi.org/10.1172/jci.insight.139783

Internet

https://doi.org/10.1172/jci.insight.139783

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