Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells
Living cells and tissues experience various complex modes of forces but how different force modes impact gene expression is elusive. Here authors apply forces via magnetic beads to integrins on a cell surface and observe force-mode dependent chromatin stretching and gene upregulation in cells and id...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18584-5 |