Biological evaluation and pharmacokinetic profiling of a coumarin-benzothiazole hybrid as a new scaffold for human gliomas

A coumarin-benzothiazole hybrid 3 was recently reported as a potential anticancer lead compound based on antioxidant and α-glucosidase inhibitory activities. Herein, we report anticancer activity of the lead compound 3 at a single dose (10 μM) against a panel of 60 cancer cell lines. Analysis of the...

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Bibliographic Details
Main Authors: Moustafa T. Gabr, Sefa Celik, Sevim Akyuz, Aysen E. Ozel
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098620300014