Targeted Thiazole Orange Derivative with Folate: Synthesis, Fluorescence and in Vivo Fluorescence Imaging

A Thiazole Orange conjugated with folate derivative was synthesized in two steps. Firstly, folate was coupled with 1-(3-aminopropyl)-4-methylquinolinium bromide to afford folate-methylquinolinium bromide, which then reacted with benzothiazolium to obtain the title folate-conjugated compound. The com...

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Bibliographic Details
Main Authors: Qingyang Meng, Baolian Zhang, Yiqi Wang, Xuening Fei, Yingchun Gu
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/10/6983/