Activation of Autophagy Protects Against ROS-Mediated Mitochondria-Dependent Apoptosis in L-02 Hepatocytes Induced by Cr(VI)

Activation of Autophagy Protects Against ROS-Mediated Mitochondria-Dependent Apoptosis in L-02 Hepatocytes Induced by Cr(VI)

Background: Hexavalent chromium (Cr(VI)) overdose causes hepatocellular injuries by inducing mitochondrial damage and subsequent apoptosis in animals and humans. Autophagy can selectively remove damaged organelles, especially impaired mitochondria, and in turn, protects against mitochondria-dependen...

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Bibliographic Details
Main Authors: Ying Xie, Fang Xiao, Lei Luo, Caigao Zhong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Autophagy
Hepatocytes
ROS
Mitochondria
Apoptosis
Online Access:http://www.karger.com/Article/FullText/358646

Internet

http://www.karger.com/Article/FullText/358646

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