Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling

Platelets have been long postulated to play a critical role in the pathogenesis of prostate cancer, although relatively little is known regarding the precise mechanisms involved. Androgen deprivation therapy (ADT) for prostate cancer eventually fails with relapse occurring in the form of castration-...

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Bibliographic Details
Main Authors: Alexander B. Zaslavsky, Audrey Gloeckner-Kalousek, Mackenzie Adams, Nagireddy Putluri, Harene Venghatakrishnan, Hangwen Li, Todd M. Morgan, Felix Y. Feng, Muneesh Tewari, Arun Sreekumar, Ganesh S. Palapattu
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861500069X