Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast.

Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast.

Although numerous regulatory connections between pre-mRNA splicing and chromatin have been demonstrated, the precise mechanisms by which chromatin factors influence spliceosome assembly and/or catalysis remain unclear. To probe the genetic network of pre-mRNA splicing in the fission yeast Schizosacc...

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Bibliographic Details
Main Authors: Kristin L Patrick, Colm J Ryan, Jiewei Xu, Jesse J Lipp, Kelly E Nissen, Assen Roguev, Michael Shales, Nevan J Krogan, Christine Guthrie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4380400?pdf=render

Internet

http://europepmc.org/articles/PMC4380400?pdf=render

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