Direct measurement of pervasive weak repression by microRNAs and their role at the network level

Direct measurement of pervasive weak repression by microRNAs and their role at the network level

Abstract Background A gene regulatory network (GRN) comprises many weak links that are often regulated by microRNAs. Since miRNAs rarely repress their target genes by more than 30%, doubts have been expressed about the biological relevance of such weak effects. These doubts raise the possibility of...

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Bibliographic Details
Main Authors: Fuqiang Ma, Pei Lin, Qingjian Chen, Xuemei Lu, Yong E. Zhang, Chung-I Wu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Genomics
Subjects:
mRNA degradation
MiR310s
Targets
Weak repression
Network
Online Access:http://link.springer.com/article/10.1186/s12864-018-4757-z

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http://link.springer.com/article/10.1186/s12864-018-4757-z

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