Molecular docking study on the α3β2 neuronal nicotinic acetylcholine receptor complexed with α-Conotoxin GIC

Molecular docking study on the α3β2 neuronal nicotinic acetylcholine receptor complexed with α-Conotoxin GIC

Nicotinic acetylcholine receptors (nAChRs) are a diverse familyof homo- or heteropentameric ligand-gated ion channels.Understanding the physiological role of each nAChR subtypeand the key residues responsible for normal and pathologicalstates is important. α-Conotoxin neuropeptides are highly select...

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Bibliographic Details
Main Authors: Chewook Lee, Si-Hyung Lee, Do-Hyoung Kim, Kyou-Hoon Han
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-05-01
Series:BMB Reports
Subjects:
α-Conotoxin GIC
Homology modeling
Ligand-docking
Molecular dynamics (MD) simulations
Nicotinic acetylcholine receptors (nAChRs)
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS01JTVEMTIwNTI0MjAwN18lMjgyNzUtMjgwJTI5Qk1CLTExLTI0NS5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS01JTVEMTIwNTI0MjAwN18lMjgyNzUtMjgwJTI5Qk1CLTExLTI0NS5wZGY=

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