Optogenetics in Mice Performing a Visual Discrimination Task: Measurement and Suppression of Retinal Activation and the Resulting Behavioral Artifact.

Optogenetic techniques are used widely to perturb and interrogate neural circuits in behaving animals, but illumination can have additional effects, such as the activation of endogenous opsins in the retina. We found that illumination, delivered deep into the brain via an optical fiber, evoked a beh...

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Bibliographic Details
Main Authors: Bethanny Danskin, Daniel Denman, Matthew Valley, Douglas Ollerenshaw, Derric Williams, Peter Groblewski, Clay Reid, Shawn Olsen, Timothy Blanche, Jack Waters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686123?pdf=render