Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells

Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells

Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired. In this respect, photoporation is a promising recent tec...

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Bibliographic Details
Main Authors: Lien Van Hoecke, Laurens Raes, Stephan Stremersch, Toon Brans, Juan C. Fraire, Ria Roelandt, Wim Declercq, Peter Vandenabeele, Koen Raemdonck, Kevin Braeckmans, Xavier Saelens
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
protein delivery
vapor nanobubble photoporation
necroptotic cell death
mixed-lineage kinase domain-like
apoptotic cell death
caspases
Online Access:https://www.mdpi.com/1422-0067/20/17/4254

Internet

https://www.mdpi.com/1422-0067/20/17/4254

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