The I-MICRO trial, Ilomedin for treatment of septic shock with persistent microperfusion defects: a double-blind, randomized controlled trial—study protocol for a randomized controlled trial

The I-MICRO trial, Ilomedin for treatment of septic shock with persistent microperfusion defects: a double-blind, randomized controlled trial—study protocol for a randomized controlled trial

Abstract Background Septic shock remains a significant cause of death in critically ill patients. During septic shock, some patients will retain microcirculatory disorders despite optimal hemodynamic support (i.e., fluid resuscitation, vasopressors, inotropes). Alterations in the microcirculation ar...

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Bibliographic Details
Main Authors: Matthieu Legrand, Hafid Ait Oufella, Daniel De Backer, Jacques Duranteau, Marc Leone, Bruno Levy, Patrick Rossignol, Eric Vicaut, François Dépret, for the I-MICRO trial investigators
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Trials
Subjects:
Sepsis
Iloprost
Prostacyclin
Vasodilator
Microcirculation
Skin mottling
Online Access:http://link.springer.com/article/10.1186/s13063-020-04549-y

Internet

http://link.springer.com/article/10.1186/s13063-020-04549-y

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