A Simple Mechanism Based on Amino Acid Substitutions is not a Critical Determinant of High Mortality of Japanese Encephalitis Virus Infection in Mice

A Simple Mechanism Based on Amino Acid Substitutions is not a Critical Determinant of High Mortality of Japanese Encephalitis Virus Infection in Mice

For the development of effective treatment strategies for Japanese encephalitis (JE), it is important to identify the viral factors causing severe disease during JE virus (JEV) infection. In this study, we assessed whether amino acid substitutions are critical factors for higher mortality of JaTH160...

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Bibliographic Details
Main Authors: Yuki Takamatsu, Leo Uchida, Muhareva Raekiansyah, Mark Anthony Luz, Kouichi Morita, Daisuke Hayasaka
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Viruses
Subjects:
Japanese encephalitis virus
pathogenicity
mouse
recombinant
amino acid substitution
Online Access:http://www.mdpi.com/1999-4915/10/2/62

Internet

http://www.mdpi.com/1999-4915/10/2/62

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