Exploring digenic inheritance in arrhythmogenic cardiomyopathy

Exploring digenic inheritance in arrhythmogenic cardiomyopathy

Abstract Background Arrhythmogenic cardiomyopathy (ACM) is an inherited genetic disorder, characterized by the substitution of heart muscle with fibro-fatty tissue and severe ventricular arrhythmias, often leading to heart failure and sudden cardiac death. ACM is considered a monogenic disorder, but...

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Bibliographic Details
Main Authors: Eva König, Claudia Béu Volpato, Benedetta Maria Motta, Hagen Blankenburg, Anne Picard, Peter Pramstaller, Michela Casella, Werner Rauhe, Giulio Pompilio, Viviana Meraviglia, Francisco S. Domingues, Elena Sommariva, Alessandra Rossini
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Medical Genetics
Subjects:
Digenic inheritance
Arrhythmogenic cardiomyopathy
Exome sequencing
ACM
PKP2
Online Access:http://link.springer.com/article/10.1186/s12881-017-0503-7

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http://link.springer.com/article/10.1186/s12881-017-0503-7

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