Immune-Related Adverse Events and Corticosteroid Use for Cancer-Related Symptoms Are Associated With Efficacy in Patients With Non-small Cell Lung Cancer Receiving Anti-PD-(L)1 Blockade Agents

Immune-Related Adverse Events and Corticosteroid Use for Cancer-Related Symptoms Are Associated With Efficacy in Patients With Non-small Cell Lung Cancer Receiving Anti-PD-(L)1 Blockade Agents

Background: Immune-related adverse events (irAEs) have been associated with improved efficacy in advanced non-small cell lung cancer (NSCLC) patients receiving anti-PD-(L)1 blockade agents, while the concurrent use of corticosteroids seems to worsen it. We evaluated outcomes in advanced NSCLC patien...

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Bibliographic Details
Main Authors: Mariona Riudavets, Joaquin Mosquera, Rosario Garcia-Campelo, Jorgina Serra, Georgia Anguera, Pablo Gallardo, Ivana Sullivan, Andrés Barba, Luís del Carpio, Agustí Barnadas, Ignasi Gich, Margarita Majem
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
immune-related adverse events
immunotherapy
advanced NSCLC
corticosteroids
efficacy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01677/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01677/full

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