Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT).

26S proteasome is a macromolecular multi-subunit complex responsible for recognizing, unfolding, and ultimately destroying proteins. It remains poorly understood how 26S proteasome activity is regulated. The present study was to investigate if AMP-activated protein kinase (AMPK) functions as a physi...

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Bibliographic Details
Main Authors: Jian Xu, Shuangxi Wang, Benoit Viollet, Ming-Hui Zou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3345026?pdf=render