Pharmacokinetics and Anti-asthmatic Potential of Non-parenterally Administered Recombinant Human Interleukin-1 Receptor Antagonist in Animal Models

The objectives of this study were to define the pharmacokinetics of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) and its effects on allergic asthma, cell adhesion molecules, and upper respiratory tract following non-parenteral administration in animals. Pharmacokinetics and immunom...

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Bibliographic Details
Main Authors: Ting Li, Wan-Liang Lu, Hai-Yan Hong, Yan-Sheng Yao, Pu Han, Zhong-Kun Li, Gui-Ling Wang, Yi Cao, Xiang-Rui Liu, Jian-Cheng Wang, Xuan Zhang, Qiang Zhang
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319343750