Interactions Between Genes From Aging Pathways May Influence Human Lifespan and Improve Animal to Human Translation

Interactions Between Genes From Aging Pathways May Influence Human Lifespan and Improve Animal to Human Translation

A major goal of aging research is identifying genetic targets that could be used to slow or reverse aging – changes in the body and extend limits of human lifespan. However, majority of genes that showed the anti-aging and pro-survival effects in animal models were not replicated in humans, with few...

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Bibliographic Details
Main Authors: Svetlana Ukraintseva, Matt Duan, Konstantin Arbeev, Deqing Wu, Olivia Bagley, Arseniy P. Yashkin, Galina Gorbunova, Igor Akushevich, Alexander Kulminski, Anatoliy Yashin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
aging pathways
animal to human translation
heterogeneity of longevity
genetic interactions
statistical epistasis
stress response
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.692020/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.692020/full

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