Comorbidity associated to Ascaris suum infection during pulmonary fibrosis exacerbates chronic lung and liver inflammation and dysfunction but not affect the parasite cycle in mice.

Comorbidity associated to Ascaris suum infection during pulmonary fibrosis exacerbates chronic lung and liver inflammation and dysfunction but not affect the parasite cycle in mice.

Ascariasis is considered the most neglected tropical disease, and is a major problem for the public health system. However, idiopathic pulmonary fibrosis (IPF) is a result of chronic extracellular deposition of matrix in the pulmonary parenchyma, and thickening of the alveolar septa, which reduces a...

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Bibliographic Details
Main Authors: Fabrício Marcus Silva Oliveira, Pablo Hemanoel da Paixão Matias, Lucas Kraemer, Ana Clara Gazzinelli-Guimarães, Flaviane Vieira Santos, Chiara Cássia Oliveira Amorim, Denise Silva Nogueira, Camila Simões Freitas, Marcelo Vidigal Caliari, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Remo Castro Russo, Ricardo Toshio Fujiwara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007896

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https://doi.org/10.1371/journal.pntd.0007896

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