Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

Olopatadine hydrochloride (olopatadine) is an antiallergic drug with histamine H1 receptor antagonistic activity. Recently, olopatadine has been shown to bind to S100A12 which is a member of the S100 family of calcium-binding proteins, and exerts multiple proinflammatory activities including chemota...

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Bibliographic Details
Main Authors: Kazuya Kishimoto, Satoshi Kaneko, Kenji Ohmori, Tadafumi Tamura, Kazuhide Hasegawa
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/MI/2006/42726