Flattop regulates basal body docking and positioning in mono- and multiciliated cells

Flattop regulates basal body docking and positioning in mono- and multiciliated cells

Planar cell polarity (PCP) regulates basal body (BB) docking and positioning during cilia formation, but the underlying mechanisms remain elusive. In this study, we investigate the uncharacterized gene Flattop (Fltp) that is transcriptionally activated during PCP acquisition in ciliated tissues. Flt...

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Bibliographic Details
Main Authors: Moritz Gegg, Anika Böttcher, Ingo Burtscher, Stefan Hasenoeder, Claude Van Campenhout, Michaela Aichler, Axel Walch, Seth G N Grant, Heiko Lickert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
basal body
spindle positioning
planar cell polarity
actin
microtubule
Flattop
Online Access:https://elifesciences.org/articles/03842

Internet

https://elifesciences.org/articles/03842

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