Progress in Allergy Signal Research on Mast Cells: Up-Regulation of Histamine Signal-Related Gene Expression in Allergy Model Rats
Brown Norway allergy model rats sensitized to toluene 2,4-diisocyanate (TDI) were developed. Histamine H1receptor mRNA level was elevated in nasal mucosa of allergy model rats after the provocation with TDI, which was followed by H1-receptor up-regulation. Elevation of histamine H1receptor mRNA was...
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319314884 |