Progress in Allergy Signal Research on Mast Cells: Up-Regulation of Histamine Signal-Related Gene Expression in Allergy Model Rats

Brown Norway allergy model rats sensitized to toluene 2,4-diisocyanate (TDI) were developed. Histamine H1receptor mRNA level was elevated in nasal mucosa of allergy model rats after the provocation with TDI, which was followed by H1-receptor up-regulation. Elevation of histamine H1receptor mRNA was...

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Bibliographic Details
Main Author: Hiroyuki Fukui
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319314884