A microfluidic-based multi-shear device for investigating the effects of low fluid-induced stresses on osteoblasts.

Interstitial fluid flow (IFF) within the extracellular matrix (ECM) produces low magnitude shear stresses on cells. Fluid flow-induced stress (FSS) plays an important role during tissue morphogenesis. To investigate the effect of low FSS generated by IFF on cells, we developed a microfluidic-based c...

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Bibliographic Details
Main Authors: Weiliang Yu, Hong Qu, Guoqing Hu, Qian Zhang, Kui Song, Haijie Guan, Tingjiao Liu, Jianhua Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3937402?pdf=render